Mosapride-d5

Mosapride-d5 is the deuterium labeled Mosapride. Mosapride is a gastroprokinetic agent that acts as a selective 5HT4 agonist.

Product Specifications

CAS Number

[1246820-66-5]

UNSPSC

12352005

Target

5-HT Receptor; Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

GPCR/G Protein; Neuronal Signaling; Others

Field of Research

Neurological Disease

Solubility

10 mM in DMSO

Smiles

FC(C=C1)=CC=C1CN(CCO2)CC2CNC(C3=C(C=C(C(Cl)=C3)N)OC([2H])([2H])C([2H])([2H])[2H])=O

Molecular Formula

C21H20D5ClFN3O3

Molecular Weight

426.92

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Tack J, et al. Systematic review: cardiovascular safety profile of 5-HT (4) agonists developed for gastrointestinal disorders. Aliment Pharmacol Ther. 2012 Apr;35 (7) :745-67.|[3]Curran MP, et al. Mosapride in gastrointestinal disorders. Drugs. 2008;68 (7) :981-91.|[4]Odaka T, et al. Serotonin 5- HT4 receptor agonist (mosapride citrate) . Nihon Rinsho. 2006 Aug;64 (8) :1491-4.