Cytidine-15N3

Cytidine-15N3 is the 15N labeled Cytidine[1]. Cytidine is a pyrimidine nucleoside and acts as a component of RNA. Cytidine is a precursor of uridine. Cytidine controls neuronal-glial glutamate cycling, affecting cerebral phospholipid metabolism, catecholamine synthesis, and mitochondrial function[2][3][4].

Product Specifications

Product Name Alternative

Cytosine β-D-riboside-15N3; Cytosine-1-β-D-ribofuranoside-15N3

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Endogenous Metabolite; Nucleoside Antimetabolite/Analog

Type

Isotope-Labeled Compounds

Related Pathways

Cell Cycle/DNA Damage; Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/cytidine-15n3.html

Purity

99.3

Solubility

10 mM in DMSO

Smiles

OC[C@@H]1[C@@H](O)[C@@H](O)[C@H]([15N]2C([15N]=C([15NH2])C=C2)=O)O1

Molecular Formula

C9H13 15N3O5

Molecular Weight

246.20

Precautions

H302, H315, H319, H335

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Jonas DA, et al. Safety considerations of DNA in food. Ann Nutr Metab. 2001;45 (6) :235-54.|[3]Wurtman RJ, et al. Effect of oral CDP-choline on plasma choline and uridine levels in humans. Biochem Pharmacol. 2000 Oct 160 (7) :989-92.|[4]Machado-Vieira R, et, al. New therapeutic targets for mood disorders. ScientificWorldJournal. 2010 Apr 1310:713-26.