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Cytidine-d2

Cytidine-d2 is the deuterium labeled Cytidine. Cytidine is a pyrimidine nucleoside and acts as a component of RNA. Cytidine is a precursor of uridine. Cytidine controls neuronal-glial glutamate cycling, affecting cerebral phospholipid metabolism, catecholamine synthesis, and mitochondrial function[1][2][3].

Product Specifications

CAS Number

40632-25-5

Product Name Alternative

Cytosine β-D-riboside-d2; Cytosine-1-β-D-ribofuranoside-d2

UNSPSC

12352005

Target

Endogenous Metabolite; Nucleoside Antimetabolite/Analog

Type

Isotope-Labeled Compounds

Related Pathways

Cell Cycle/DNA Damage; Metabolic Enzyme/Protease

Field of Research

Neurological Disease

Purity

99.86

Solubility

10 mM in DMSO|DMSO : 50mg/mL (ultrasonic) |H2O : ≥ 50mg/mL

Smiles

OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N2C(N=C(N)C([2H])=C2[2H])=O)O1

Molecular Formula

C9H11D2N3O5

Molecular Weight

245.23

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Machado-Vieira R, et, al. New therapeutic targets for mood disorders. ScientificWorldJournal. 2010 Apr 13;10:713-26.|[3]Jonas DA, et al. Safety considerations of DNA in food. Ann Nutr Metab. 2001;45 (6) :235-54.|[4]Wurtman RJ, et al. Effect of oral CDP-choline on plasma choline and uridine levels in humans. Biochem Pharmacol. 2000 Oct 1;60 (7) :989-92.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Isotope-Labeled Compounds

Clinical Information

No Development Reported

Frequently Asked Questions

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