Adenine-15N5

Adenine-15N5 (6-Aminopurine-15N5; Vitamin B4-15N5) is 15N labeled Adenine (HY-B0152) . Adenine (6-Aminopurine), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine acts as a chemical component of DNA and RNA. Adenine also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis.

Product Specifications

Product Name Alternative

6-Aminopurine-15N5; Vitamin B4-15N5

UNSPSC

12352005

Target

DNA/RNA Synthesis; Endogenous Metabolite; Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/adenine-15n5.html

Purity

95.0

Solubility

10 mM in DMSO

Smiles

[15NH2]C1=[15N]C=[15N]C2=C1[15N]=C[15NH]2

Molecular Formula

C5H5 15N5

Molecular Weight

140.09

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]ORO J, et al. Synthesis of purines under possible primitive earth conditions. I. Adenine from hydrogen cyanide. Arch Biochem Biophys. 1961 Aug;94:217-27.|[3]Griffiths AJF, et al. An Introduction to Genetic Analysis. 7th edition. New York: W. H. Freeman; 2000. Structure of DNA.|[4]Reader V. The assay of vitamin B (4) . Biochem J. 1930;24 (6) :1827-31.