Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Niacin-15N,13C3

Product Specifications

UNSPSC Description

Niacin-15N,13C3 is the 13C and 15N labeled Niacin[1]. Niacin (Vitamin B3) is an orally active water-soluble B3 vitamin that is an essential nutrient for humans. Niacin (Vitamin B3) plays a key role in energy metabolism, cell signaling cascades regulating gene expression and apoptosis. Niacin (Vitamin B3) is also used in the study of cardiovascular diseases[2][3].

Target Antigen

Autophagy; Endogenous Metabolite

Type

Isotope-Labeled Compounds

Related Pathways

Autophagy;Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/niacin-15n-13c3.html

Solubility

10 mM in DMSO

Smiles

O[13C](C1=[13CH][15N]=[13CH]C=C1)=O

Molecular Weight

127.08

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.|[2]Bruckert E, et al. Meta-analysis of the effect of nicotinic acid alone or in combination on cardiovascular events and atherosclerosis. Atherosclerosis. 2010 Jun;210(2):353-61.|[3]Wan P, et al. Pellagra: a review with emphasis on photosensitivity. Br J Dermatol. 2011 Jun164(6):1188-200.|[4]Ishii N, et al. Pellagra among chronic alcoholics: clinical and pathological study of 20 necropsy cases. J Neurol Neurosurg Psychiatry. 1981 Mar44(3):209-15.|[5]Areeg M Almubarak, et al. Supplementation with Niacin during in vitro maturation improves the quality of porcine embryos. Theriogenology. 2021 Jul 15169:36-46. doi: 10.1016/j.theriogenology.2021.04.005. Epub 2021 Apr 18.|[6]Nobuhiro Hirakawa, et al. Anti-invasive activity of niacin and trigonelline against cancer cells. Biosci Biotechnol Biochem. 2005 Mar69(3):653-8.|[7]Kang Cheng, et al. Antagonism of the prostaglandin D2 receptor 1 suppresses nicotinic acid-induced vasodilation in mice and humans. Proc Natl Acad Sci U S A. 2006 Apr 25103(17):6682-7.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-B0143S4/Niacin-15N-13C3-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-B0143S4/

Clinical Information

No Development Reported

CAS Number

2483829-87-2

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

Rabbit Polyclonal ATP6V1B2 Antibody
NBP3-38048-100ul 100 µL

Rabbit Polyclonal ATP6V1B2 Antibody

Ask
View Details
Rabbit Polyclonal PARG1 Antibody [Alexa Fluor 594]
NBP1-05989AF594 0.1 mL

Rabbit Polyclonal PARG1 Antibody [Alexa Fluor 594]

Ask
View Details
ZNF266 Antibody, Biotin conjugated
A38846-100UG 100 µg

ZNF266 Antibody, Biotin conjugated

Ask
View Details