Estradiol (hemihydrate)

Estradiol (β-Estradiol) hemihydrate is a steroid hormone and the major female sex hormone. Estradiol (β-Estradiol) hemihydrate can up-regulate the expression of neural markers of human endometrial stem cells (hEnSCs) and promote their neural differentiation. Estradiol (β-Estradiol) hemihydrate can be used for the research of cancers, neurodegenerative diseases and neural tissue engineering[1][2].

Product Specifications

CAS Number

[35380-71-3]

Product Name Alternative

β-Estradiol (hemihydrate) ; 17β-Estradiol (hemihydrate) ; 17β-Oestradiol (hemihydrate)

UNSPSC

12352005

Hazard Statement

H351, H360, H362, H410

Target

Bacterial; Endogenous Metabolite; Estrogen Receptor/ERR

Type

Natural Products

Related Pathways

Anti-infection; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

Applications

Cancer-programmed cell death

Field of Research

Cancer; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/estradiol-hemihydrate.html

Purity

99.79

Solubility

DMSO : ≥ 100 mg/mL

Smiles

C[C@@]12[C@](CC[C@@H]2O)([H])[C@@]3([H])[C@@](CC1)([H])C4=CC=C(O)C=C4CC3.O.[1/2]

Molecular Formula

C18H24O2·1/2H2O

Molecular Weight

281.39

Precautions

H351, H360, H362, H410

References & Citations

[1]Elham Hasanzadeh. Defining the role of 17β-estradiol in human endometrial stem cells differentiation into neuron-like cells. Cell Biol Int. 2021 Jan;45 (1) :140-153.|[2]Yujiao Lu, et al. Neuron-Derived Estrogen Regulates Synaptic Plasticity and Memory. J Neurosci. 2019 Apr 10;39 (15) :2792-2809.