Flucytosine-13C,15N2

Flucytosine-13C,15N2 (NSC 103805-13C,15N2; Ro 2-9915-13C,15N2) is a 13C- and 15N-labeled Flucytosine (HY-B0139) .

Product Specifications

CAS Number

[1216616-31-7]

Product Name Alternative

5-Fluorocytosine-13C,15N2; NSC 103805-13C,15N2; Ro 2-9915-13C,15N2

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Antibiotic; Fungal; Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

Anti-infection; Others

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/flucytosine-13c-15n2.html

Purity

98.06

Solubility

10 mM in DMSO

Smiles

NC1=C(C=[15N][13C]([15NH]1)=O)F

Molecular Formula

C3 13CH4FN 15N2O

Molecular Weight

132.07

Precautions

H302, H315, H319, H335

References & Citations

[1]Vermes A, et al. Flucytosine: a review of its pharmacology, clinical indications, pharmacokinetics, toxicity and drug interactions. J Antimicrob Chemother. 2000 Aug;46 (2) :171-9.|[2]Te Dorsthorst DT, et al. In vitro interaction of flucytosine combined with amphotericin B or fluconazole against thirty-five yeast isolates determined by both the fractional inhibitory concentration index and the response surface approach. Antimicrob Agents Chemother. 2002 Sep;46 (9) :2982-9.|[3]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-246.