Aztreonam-d6

Aztreonam-d6 is deuterium labeled Aztreonam. Aztreonam (SQ-26,776) is a synthetic monocyclic beta-lactam antibiotic, which has a very high affinity for penicillin-binding protein 3 (PBP-3) .

Product Specifications

CAS Number

[1127452-94-1]

Product Name Alternative

SQ-26,776-d6

UNSPSC

12352005

Target

Antibiotic; Bacterial; Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

Anti-infection; Others

Applications

COVID-19-immunoregulation

Field of Research

Infection

Purity

99.29

Solubility

10 mM in DMSO

Smiles

OC(C(C([2H])([2H])[2H])(C([2H])([2H])[2H])O/N=C(C1=CSC(N)=N1)\C(N[C@H]2[C@@H](N(C2=O)S(=O)(O)=O)C)=O)=O

Molecular Formula

C13H11D6N5O8S2

Molecular Weight

441.47

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Guay DR, et al. Aztreonam, a new monobactam antimicrobial. Clin Pharm. 1985 Sep-Oct;4 (5) :516-26.|[3]Kobayashi Y, et al. Synergy with aztreonam and arbekacin or tobramycin against Pseudomonas aeruginosa isolated from blood. J Antimicrob Chemother. 1992 Dec;30 (6) :871-2.