(-) -Ketoconazole-d3
(-) -Ketoconazole-d3 is deuterium labeled (-) -Ketoconazole. (-) -Ketoconazole ((-) -R 41400) is one of the enantiomer of Ketoconazole. Ketoconazole is a racemic mixture of two enantiomers, levoketoconazole ((2S,4R) - (−) -ketoconazole) and dextroketoconazole ((2R,4S) - (+) -ketoconazole) .
Product Specifications
CAS Number
[1217766-70-5]
Product Name Alternative
(-) -Ketoconazol-d3; (-) -R 41400-d3
UNSPSC
12352005
Hazard Statement
H301-H360-H373-H400-H410
Target
Fungal; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Anti-infection; Others
Applications
COVID-19-immunoregulation
Field of Research
Infection; Inflammation/Immunology
Solubility
10 mM in DMSO
Smiles
[2H]C([2H])([2H])C(N(CC1)CCN1C(C=C2)=CC=C2OC[C@H](CO3)O[C@@]3(C4=C(C=C(C=C4)Cl)Cl)CN5C=CN=C5)=O
Molecular Formula
C26H25D3Cl2N4O4
Molecular Weight
534.45
Precautions
P260-P264-P270-P273-P280-P330-P391-P405-P501
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
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