Doxofylline-d6
Product Specifications
UNSPSC Description
Doxofylline-d6 is the deuterium labeled Doxofylline. Doxofylline is an antagonist of adenosine A1 receptor which also inhibits phosphodiesterase IV.
Target Antigen
Adenosine Receptor; Phosphodiesterase (PDE)
Type
Isotope-Labeled Compounds
Related Pathways
GPCR/G Protein;Metabolic Enzyme/Protease
Field of Research
Inflammation/Immunology
Purity
99.0
Solubility
10 mM in DMSO
Smiles
O=C1C2=C(N=CN2CC3OCCO3)N(C([2H])([2H])[2H])C(N1C([2H])([2H])[2H])=O
Molecular Weight
272.29
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. |[2]Shukla D, et al. Doxofylline: a promising methylxanthine derivative for the treatment of asthma and chronic obstructive pulmonary disease. Expert Opin Pharmacother. 2009 Oct;10(14):2343-56.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Clinical Information
No Development Reported
CAS Number
1219805-99-8
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