Doxofylline-d6
Doxofylline-d6 is the deuterium labeled Doxofylline. Doxofylline is an antagonist of adenosine A1 receptor which also inhibits phosphodiesterase IV.
Product Specifications
CAS Number
1219805-99-8
UNSPSC
12352005
Target
Adenosine Receptor; Phosphodiesterase (PDE)
Type
Isotope-Labeled Compounds
Related Pathways
GPCR/G Protein; Metabolic Enzyme/Protease
Field of Research
Inflammation/Immunology
Purity
99.61
Solubility
10 mM in DMSO|DMSO : 50mg/mL (ultrasonic) |H2O : 25mg/mL (ultrasonic)
Smiles
O=C1C2=C(N=CN2CC3OCCO3)N(C([2H])([2H])[2H])C(N1C([2H])([2H])[2H])=O
Molecular Formula
C11H8D6N4O4
Molecular Weight
272.29
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Shukla D, et al. Doxofylline: a promising methylxanthine derivative for the treatment of asthma and chronic obstructive pulmonary disease. Expert Opin Pharmacother. 2009 Oct;10 (14) :2343-56.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Frequently Asked Questions
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