Roslin 2 (bromide)
Product Specifications
UNSPSC Description
Roslin 2 bromide (Benzylhexamethylenetetramine bromide) is a p53 reactivator with anticancer effects. Roslin 2 bromide binds FAK, disrupts the binding of FAK and p53[1].
Target Antigen
FAK; MDM-2/p53
Type
Reference compound
Related Pathways
Apoptosis;Protein Tyrosine Kinase/RTK
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/roslin-2-bromide.html
Purity
99.0
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
[N@@]12C[N+](C[N@](C3)C1)(C[N@@]3C2)CC4=CC=CC=C4.[Br-]
Molecular Weight
311.22
References & Citations
[1]Vita M Golubovskaya, et al. Disruption of focal adhesion kinase and p53 interaction with small molecule compound R2 reactivated p53 and blocked tumor growth. BMC Cancer. 2013 Jul 11;13:342.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-A0280/Roslin-2-bromide-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-A0280/Roslin-2-bromide-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
29574-21-8
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