Roslin 2 (bromide)

Roslin 2 bromide (Benzylhexamethylenetetramine bromide) is a p53 reactivator with anticancer effects. Roslin 2 bromide binds FAK, disrupts the binding of FAK and p53[1].

Product Specifications

CAS Number

[29574-21-8]

Product Name Alternative

Benzylhexamethylenetetramine (bromide)

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

FAK; MDM-2/p53

Type

Reference compound

Related Pathways

Apoptosis; Protein Tyrosine Kinase/RTK

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/roslin-2-bromide.html

Purity

99.0

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

[N@@]12C[N+](C[N@](C3)C1)(C[N@@]3C2)CC4=CC=CC=C4.[Br-]

Molecular Formula

C13H19BrN4

Molecular Weight

311.22

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Vita M Golubovskaya, et al. Disruption of focal adhesion kinase and p53 interaction with small molecule compound R2 reactivated p53 and blocked tumor growth. BMC Cancer. 2013 Jul 11;13:342.