Spirapril (hydrochloride)
Spirapril (SCH 33844) hydrochloride is a potent angiotensin converting enzyme (ACE) inhibitor with antihypertensive activity. Spirapril competitively binds to ACE and prevents the conversion of angiotensin I to angiotensin II. Spirapril is an orally active proagent of Spiraprilat and can be used for the research of hypertension, congestive heart failure[1].
Product Specifications
CAS Number
[94841-17-5]
Product Name Alternative
SCH 33844 (hydrochloride)
UNSPSC
12352005
Hazard Statement
H302, H312, H332
Target
Angiotensin-converting Enzyme (ACE)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/spirapril-hydrochloride.html
Purity
99.2
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C([C@H](C1)N(C([C@@H](N[C@H](C(OCC)=O)CCC2=CC=CC=C2)C)=O)CC31SCCS3)O.[H]Cl
Molecular Formula
C22H31ClN2O5S2
Molecular Weight
503.07
Precautions
H302, H312, H332
References & Citations
[1]Spirapril. Drugbank.|[2]B Maul, et al. Alcohol consumption is controlled by angiotensin II. FASEB J
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
Launched
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