Doxacurium (chloride)

Doxacurium chloride (BW A938U) is a potent non-depolarizing neuromuscular blocking agent. Doxacurium chloride binds to cholinergic receptors to antagonize acetylcholine, resulting in a block of neuromuscular transmission. Doxacurium chloride can be used for the research of neurological diseases[1].

Product Specifications

CAS Number

[106819-53-8]

Product Name Alternative

BW-A 938U; Nuromax

UNSPSC

12352005

Hazard Statement

H315-H319-H320

Target

NAChR

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/doxacurium-chloride.html

Solubility

10 mM in DMSO

Smiles

C[N+](CCC1=CC(OC)=C2OC)(C(CC3=CC(OC)=C(C(OC)=C3)OC)C1=C2OC)CCCOC(CCC(OCCC[N+](CCC4=CC(OC)=C(C(OC)=C54)OC)(C)C5CC6=CC(OC)=C(C(OC)=C6)OC)=O)=O.[Cl-].[Cl-]

Molecular Formula

C56H78Cl2N2O16

Molecular Weight

1106.13

Precautions

P264-P280-P302+P352-P305+P351+P338-P362

References & Citations

[1]Basta SJ, et, al. Clinical pharmacology of doxacurium chloride. A new long-acting nondepolarizing muscle relaxant. Anesthesiology. 1988 Oct;69 (4) :478-86.