Adenosine monophosphate-13C10 (dilithium)

Adenosine monophosphate-13C10 (AMP-13C10) dilithium is 13C-labeled Adenosine monophosphate (HY-A0181) . Adenosine monophosphate is an adenosine A1 receptor agonist. Adenosine monophosphate has significant antiviral activity against HSV-1 and HSV-2. Adenosine monophosphate is a key cellular metabolite regulating energy homeostasis and signal transduction[1][2][3].

Product Specifications

Product Name Alternative

AMP-13C10 (dilithium)

UNSPSC

12352005

Target

Adenosine Receptor; Endogenous Metabolite; HSV; Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

Anti-infection; GPCR/G Protein; Metabolic Enzyme/Protease; Others

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Infection; Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/adenosine-monophosphate-13c10-dilithium.html

Concentration

100 mM in 27.1 μL Tris HCl/H2O buffer pH=7.5

Purity

99.20

Solubility

10 mM in DMSO

Smiles

O=P(O[Li])(O[Li])O[13CH2][13C@H]1O[13C@@H](N2[13C]3=N[13CH]=N[13C](N)=[13C]3N=[13CH]2)[13C@H](O)[13C@@H]1O

Molecular Formula

13C10H12Li2N5O7P

Molecular Weight

369.01

References & Citations

[1]Rittiner JE, et al. AMP is an adenosine A1 receptor agonist. J Biol Chem. 2012 Feb 17;287 (8) :5301-9. |[2]Zhan Y, et al. Adenosine 5'-monophosphate ameliorates D-galactosamine/lipopolysaccharide-induced liver injury through an adenosine receptor-independent mechanism in mice. Cell Death Dis. 2014 Jan 9;5:e985. |[3]Ayisi NK, et al. Comparison of the antiviral effects of 5-methoxymethyldeoxyuridine-5'-monophosphate with adenine arabinoside-5'-monophosphate. Antiviral Res. 1983 Sep;3 (3) :161-74.