Adenosine monophosphate-13C10,15N5 (dilithium)

Adenosine monophosphate-13C10,15N5 (AMP-13C10,15N5) is the 13C-labeled and 15N-labeled Adenosine monophosphate (HY-A0181) . Adenosine monophosphate is an adenosine A1 receptor agonist. Adenosine monophosphate has significant antiviral activity against HSV-1 and HSV-2. Adenosine monophosphate is a key cellular metabolite regulating energy homeostasis and signal transduction[1][2][3].

Product Specifications

Product Name Alternative

AMP-13C10,15N5 (dilithium)

UNSPSC

12352005

Target

Adenosine Receptor; Endogenous Metabolite; HSV; Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

Anti-infection; GPCR/G Protein; Metabolic Enzyme/Protease; Others

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Infection; Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/adenosine-monophosphate-13c10-15n5.html

Concentration

100 mM in 26.74 μL Tris HCl buffer pH=7.5

Purity

99.0

Solubility

DMSO : 16.67mg/mL (ultrasonic) |H2O : 1.67mg/mL (ultrasonic)

Smiles

OP(O[13CH2][13C@H]1O[13C@@H]([15N]2[13CH]=[15N][13C]3=[13C]2[15N]=[13CH][15N]=[13C]3[15NH2])[13C@H](O[Li])[13C@@H]1O[Li])(O)=O

Molecular Formula

13C10H12Li2 15N5O7P

Molecular Weight

373.98

References & Citations

[1]Rittiner JE, et al. AMP is an adenosine A1 receptor agonist. J Biol Chem. 2012 Feb 17;287 (8) :5301-9. |[2]Zhan Y, et al. Adenosine 5'-monophosphate ameliorates D-galactosamine/lipopolysaccharide-induced liver injury through an adenosine receptor-independent mechanism in mice. Cell Death Dis. 2014 Jan 9;5:e985. |[3]Ayisi NK, et al. Comparison of the antiviral effects of 5-methoxymethyldeoxyuridine-5'-monophosphate with adenine arabinoside-5'-monophosphate. Antiviral Res. 1983 Sep;3 (3) :161-74.