Adenosine monophosphate-13C10,15N5 (disodium)

Adenosine monophosphate-13C10,15N5 (AMP-13C10,15N5) disodium is 13C and 15N-labeled Adenosine monophosphate (HY-A0181) . Adenosine monophosphate is an adenosine A1 receptor agonist. Adenosine monophosphate has significant antiviral activity against HSV-1 and HSV-2. Adenosine monophosphate is a key cellular metabolite regulating energy homeostasis and signal transduction[1][2][3].

Product Specifications

Product Name Alternative

AMP-13C10,15N5 (disodium)

UNSPSC

12352005

Target

Adenosine Receptor; Endogenous Metabolite; HSV; Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

Anti-infection; GPCR/G Protein; Metabolic Enzyme/Protease; Others

Applications

COVID-19-immunoregulation

Field of Research

Infection; Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/adenosine-monophosphate-13c10-15n5-disodium.html

Concentration

100 mM in 25.19 μL Tris HCl/H2O buffer

Purity

99.24

Solubility

10 mM in DMSO|DMSO : 125mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O[13C@@H]1[13C@H](O)[13C@@H]([13CH2]OP(O[Na])(O[Na])=O)O[13C@H]1[15N]2[13CH]=[15N][13C]3=[13C]2[15N]=[13CH][15N]=[13C]3[15NH2]

Molecular Formula

13C10H12 15N5Na2O7P

Molecular Weight

406.08

References & Citations

[1]Rittiner JE, et al. AMP is an adenosine A1 receptor agonist. J Biol Chem. 2012 Feb 17;287 (8) :5301-9. |[2]Zhan Y, et al. Adenosine 5'-monophosphate ameliorates D-galactosamine/lipopolysaccharide-induced liver injury through an adenosine receptor-independent mechanism in mice. Cell Death Dis. 2014 Jan 9;5:e985. |[3]Ayisi NK, et al. Comparison of the antiviral effects of 5-methoxymethyldeoxyuridine-5'-monophosphate with adenine arabinoside-5'-monophosphate. Antiviral Res. 1983 Sep;3 (3) :161-74.