Halofantrine
Halofantrine (SKF-102886 free base) is a highly lipophilic antimalarial active against Chloroquine-resistant strains of Plasmodium falciparum[1]. Halofantrine blocks HERG potassium channels[2].
Product Specifications
CAS Number
[69756-53-2]
Product Name Alternative
SKF-102886 (free base) ; WR-171669
UNSPSC
12352005
Hazard Statement
H315-H319-H320
Target
Parasite; Potassium Channel
Type
Reference compound
Related Pathways
Anti-infection; Membrane Transporter/Ion Channel
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/halofantrine.html
Solubility
10 mM in DMSO
Smiles
OC(CCN(CCCC)CCCC)C1=CC2=C(Cl)C=C(Cl)C=C2C3=CC(C(F)(F)F)=CC=C31
Molecular Formula
C26H30Cl2F3NO
Molecular Weight
500.42
Precautions
P264-P280-P302+P352-P305+P351+P338-P362
References & Citations
Plasmodium falciparum
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
Plasmodium
Curated Selection
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