Dihomo-γ-linolenic acid (sodium)

Dihomo-γ-linolenic acid (DGLA; all-cis-8,11,14-Eicosatrienoic acid) sodium is a 20-carbon ω-6 fatty acid, with anti-inflammatory and anti-proliferative activities. Dihomo-γ-linolenic acid (sodium) attenuates atherosclerosis in the apolipoprotein E deficient mouse model system[1][2][3].

Product Specifications

CAS Number

[65881-87-0]

Product Name Alternative

DGLA (sodium) ; all-cis-8,11,14-Eicosatrienoic acid (sodium)

UNSPSC

12352211

Target

Endogenous Metabolite

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Inflammation/Immunology; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/dihomo-γ-linolenic-acid-sodium.html

Purity

99.0

Solubility

10 mM in DMSO

Smiles

CCCCC/C=C\C/C=C\C/C=C\CCCCCCC(O[Na])=O

Molecular Formula

C20H33NaO2

Molecular Weight

328.46

References & Citations

[1]Wang X, et al. Multiple roles of dihomo-γ-linolenic acid against proliferation diseases. Lipids Health Dis. 2012 Feb 14;11:25.|[2]Wang X, et al. Multiple roles of dihomo-γ-linolenic acid against proliferation diseases. Lipids Health Dis. 2012 Feb 14;11:25.|[3]Gallagher H, et al. Dihomo-γ-linolenic acid inhibits several key cellular processes associated with atherosclerosis. Biochim Biophys Acta Mol Basis Dis. 2019 Sep 1;1865 (9) :2538-2550.|[4]Gallagher H, et al. Dihomo-γ-linolenic acid inhibits several key cellular processes associated with atherosclerosis. Biochim Biophys Acta Mol Basis Dis. 2019 Sep 1;1865 (9) :2538-2550.