Teicoplanin (sodium)
Teicoplanin sodium is a glycopeptide antibiotic indicated for use in serious infections caused by Gram-positive bacteria, including Methicillin-resistant Staphylococcus aureus and Enterococcus aureus.Teicoplanin sodium shows antiviral activity for HIV-1, SARS-CoV1 and SARS-CoV2. Teicoplanin sodium shows anti-MRSA activity[1][2].
Product Specifications
CAS Number
184539-13-7
Product Name Alternative
Antibiotic MDL-507 (sodium) ; MDL-507 (sodium)
UNSPSC
12352005
Target
Antibiotic; HIV; SARS-CoV
Type
Natural Products
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/teicoplanin-sodium.html
Solubility
10 mM in DMSO
Smiles
ClC1=C(OC2=CC3=CC(OC4=CC=C5C=C4Cl)=C2O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6[N][R])C=CC([C@H]([C@@H]7NC([C@](C8=CC(C9=C([C@H](C(O)=O)NC7=O)C=C(O)C=C9O[C@@H]%10[C@@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O%10)=C(O)C=C8)([H])NC([C@]3([H])NC([C@@](C%11=CC(O)=CC(OC%12=C(O)C=CC([C@@H](N)C%13=O)=C%12)=C%11)([H])NC([C@@H](N%13)C5)=O)=O)=O)=O)O[C@@H]%14O[C@H](CO)[C@@H](O)[C@H](O)[C@H]%14NC(C)=O)=C1.CCCCC/C=C/CCC([R])=O.CC(C)CCCCCCC([R])=O.CCCCCCCCCC([R])=O.CCC(C)CCCCCCC([R])=O.CC(C)CCCCCCCC([R])=O.[Na]
Molecular Weight
1564.3-1907.7
References & Citations
[1]Vimberg V. Teicoplanin-A New Use for an Old Drug in the COVID-19 Era? Pharmaceuticals (Basel) . 2021 Nov 26;14 (12) :1227.|[2]Ramos-Martín V, et al. Pharmacodynamics of teicoplanin against MRSA. J Antimicrob Chemother. 2017 Dec 1;72 (12) :3382-3389.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
Phase 4
Isoform
Glycopeptide
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