Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Galanthamine (hydrobromide) (Standard)

Galanthamine (hydrobromide) (Standard) is the analytical standard of Galanthamine (hydrobromide) . This product is intended for research and analytical applications. Galanthamine hydrobromide (Galantamine hydrobromide) is a selective, reversible, competitive, alkaloid AChE inhibitor, with an IC50 of 0.35 µM. Galanthamine hydrobromide is a potent allosteric potentiating ligand (APL) of human α3β4, α4β2, α6β4 nicotinic receptors (nAChRs) . Galanthamine hydrobromide is developed for the research of Alzheimer's disease (AD) [1][2][3].

Product Specifications

CAS Number

1953-04-4

Product Name Alternative

Galantamine (hydrobromide) (Standard)

UNSPSC

12352005

Target

Cholinesterase (ChE) ; nAChR; Reference Standards

Type

Reference Standards

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling; Others

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/galanthamine-hydrobromide-standard.html

Solubility

10 mM in DMSO

Smiles

O[C@@H]1C[C@@H]2OC3=C4C(CN(C)CC[C@]42C=C1)=CC=C3OC.Br

Molecular Formula

C17H22BrNO3

Molecular Weight

368.27

References & Citations

[1]L J Scott, et al. Galantamine: a review of its use in Alzheimer's disease. Drugs. 2000 Nov;60 (5) :1095-122.|[2]Marek Samochocki, et al. Galantamine is an allosterically potentiating ligand of neuronal nicotinic but not of muscarinic acetylcholine receptors. Pharmacol Exp Ther. 2003 Jun;305 (3) :1024-36.|[3]Acharya Balkrishna, et al. Anti-Acetylcholinesterase Activities of Mono-Herbal Extracts and Exhibited Synergistic Effects of the Phytoconstituents: A Biochemical and Computational Study. Molecules. 2019 Nov; 24 (22) : 4175.|[4]Balpreet Matharu, et al. Galantamine inhibits beta-amyloid aggregation and cytotoxicity. J Neurol Sci. 2009 May 15;280 (1-2) :49-58.|[5]Debby Van Dam, et al. Symptomatic effect of donepezil, rivastigmine, galantamine and memantine on cognitive deficits in the APP23 model. Psychopharmacology (Berl) . 2005 Jun;180 (1) :177-90.|[6]Johan Monbaliu, et al. Pharmacokinetics of galantamine, a cholinesterase inhibitor, in several animal species. Arzneimittelforschung. 2003;53 (7) :486-95.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Clinical Information

Launched

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Anti-APP-1/PABPC4 Antibody Picoband®, Carrier-free
A07960-2-carrier-free 100 µg/Vial

Anti-APP-1/PABPC4 Antibody Picoband®, Carrier-free

Sign In for Pricing
View Details
Lentiviral mouse Kmt2c shRNA (UAS) - Lentiviral mouse Kmt2c shRNA (UAS, RFP) (25)
GTR15234227 1 Vial

Lentiviral mouse Kmt2c shRNA (UAS) - Lentiviral mouse Kmt2c shRNA (UAS, RFP) (25)

Sign In for Pricing
View Details
5’-O-DMTr-5-iodo-2’-dU-3’-CED phosphoramidite
HY-154721-01 25 mg

5’-O-DMTr-5-iodo-2’-dU-3’-CED phosphoramidite

Sign In for Pricing
View Details
5’-O-DMTr-5-iodo-2’-dU-3’-CED phosphoramidite
HY-154721-02 50 mg

5’-O-DMTr-5-iodo-2’-dU-3’-CED phosphoramidite

Sign In for Pricing
View Details
5’-O-DMTr-5-iodo-2’-dU-3’-CED phosphoramidite
HY-154721-03 100 mg

5’-O-DMTr-5-iodo-2’-dU-3’-CED phosphoramidite

Sign In for Pricing
View Details
MDH1 Knockout Hela Polyclonal Cells
ARG9098 1 Million

MDH1 Knockout Hela Polyclonal Cells

Sign In for Pricing
View Details