(R, S, S, S, R) -Boc-Dap-NE
(R, S, S, S, R) -Boc-Dap-NE is an isomer of the dipeptide Boc-Dap-NE. Boc-Dap-NE is an intermediate in the synthesis of Monomethyl auristatin E (HY-15162), which is an inhibitor of tubulin polymerization. Monomethyl auristatin E can be used to synthesize Antibody-Drug Conjugates (ADCs) as ADC Cytotoxin.
Product Specifications
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Drug Intermediate
Type
Reference compound
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/r-s-s-s-r-boc-dap-ne.html
Purity
99.56
Solubility
10 mM in DMSO
Smiles
O=C([C@@H](C)[C@H](OC)[C@@H]1N(C(OC(C)(C)C)=O)CCC1)N[C@H](C)[C@@H](O)C2=CC=CC=C2
Molecular Formula
C23H36N2O5
Molecular Weight
420.54
Precautions
H302, H315, H319, H335
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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