MC-Val-Cit-PAB (GMP)
MC-Val-Cit-PAB GMP is a GMP grade MC-Val-Cit-PAB (HY-78738) . MC-Val-Cit-PAB is an intermediate in the synthesis of VcMMAE (HY-15575), which is a Drug-Linker Conjugates for ADC. Monomethyl auristatin E can be used to inhibit Microtubule/Tubulin as ADC Cytotoxin.
Product Specifications
CAS Number
[159857-80-4]
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
ADC Linker
Type
GMP Small Molecules
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mc-val-cit-pab-gmp.html
Solubility
10 mM in DMSO
Smiles
CC(C)[C@@H](C(N[C@@H](CCCNC(N)=O)C(NC1=CC=C(CO)C=C1)=O)=O)NC(CCCCCN2C(C=CC2=O)=O)=O
Molecular Formula
C28H40N6O7
Molecular Weight
572.65
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Anti-cd70 antibody-drug conjugates and their use for the treatment of cancer and immune disorders
Shipping Conditions
Room temperature
Scientific Category
GMP Small Molecules
Clinical Information
No Development Reported
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