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MC-Val-Cit-PAB (GMP)

MC-Val-Cit-PAB GMP is a GMP grade MC-Val-Cit-PAB (HY-78738) . MC-Val-Cit-PAB is an intermediate in the synthesis of VcMMAE (HY-15575), which is a Drug-Linker Conjugates for ADC. Monomethyl auristatin E can be used to inhibit Microtubule/Tubulin as ADC Cytotoxin.

Product Specifications

CAS Number

[159857-80-4]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

ADC Linker

Type

GMP Small Molecules

Related Pathways

Antibody-drug Conjugate/ADC Related

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/mc-val-cit-pab-gmp.html

Solubility

10 mM in DMSO

Smiles

CC(C)[C@@H](C(N[C@@H](CCCNC(N)=O)C(NC1=CC=C(CO)C=C1)=O)=O)NC(CCCCCN2C(C=CC2=O)=O)=O

Molecular Formula

C28H40N6O7

Molecular Weight

572.65

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Anti-cd70 antibody-drug conjugates and their use for the treatment of cancer and immune disorders

Shipping Conditions

Room temperature

Scientific Category

GMP Small Molecules

Clinical Information

No Development Reported

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