Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Ibuprofen-13C, d3

Ibuprofen-13C, d3 is the 13C- and deuterium labeled Ibuprofen. Ibuprofen is an anti-inflammatory agent targeting COX-1 and COX-2 with IC50s of 13 μM and 370 μM, respectively[1].

Product Specifications

CAS Number

1261394-40-4

Product Name Alternative

(±) -Ibuprofen-13C, d3

UNSPSC

12352005

Hazard Statement

H302

Target

Apoptosis; COX; Isotope-Labeled Compounds; Parasite

Type

Isotope-Labeled Compounds

Related Pathways

Anti-infection; Apoptosis; Immunology/Inflammation; Others

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology; Cancer

Solubility

10 mM in DMSO

Smiles

OC(C(C1=CC=C(C=C1)CC(C)C)[13C]([2H])([2H])[2H])=O

Molecular Formula

C12 13CH15D3O2

Molecular Weight

210.29

Precautions

P264-P270-P330-P501

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-223.|[2]Driban JB, et al. Joint inflammation and early degeneration induced by high-force reaching are attenuated by ibuprofen in an animal model of work-related musculoskeletal disorder. J Biomed Biotechnol. 2011;2011:691412|[3]Khwaja F, et al. Ibuprofen inhibits survival of bladder cancer cells by induced expression of the p75NTR tumor suppressor protein. Cancer Res. 2004 Sep 1;64 (17) :6207-13.|[4]Noreen Y, et al. Development of a radiochemical cyclooxygenase-1 and -2 in vitro assay for identification of natural products as inhibitors of prostaglandin biosynthesis. J Nat Prod. 1998 Jan;61 (1) :2-7.|[5]Palayoor ST, et al. Constitutive activation of IkappaB kinase alpha and NF-kappaB in prostate cancer cells is inhibited by ibuprofen. Oncogene. 1999 Dec 2;18 (51) :7389-94.|[6]Rao GH, et al. Ibuprofen protects platelet cyclooxygenase from irreversible inhibition by aspirin. Arteriosclerosis. 1983 Jul-Aug;3 (4) :383-8.

Shipping Conditions

Room temperature

Scientific Category

Isotope-Labeled Compounds

Clinical Information

No Development Reported

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

ANXA5 Adenovirus (Rat)
12076056 1.0 mL

ANXA5 Adenovirus (Rat)

Sign In for Pricing
View Details
Mouse Interleukin-11 ELISA Kit
MBS2884259-01 48 Well

Mouse Interleukin-11 ELISA Kit

Sign In for Pricing
View Details
Mouse Interleukin-11 ELISA Kit
MBS2884259-02 96 Well

Mouse Interleukin-11 ELISA Kit

Sign In for Pricing
View Details
Mouse Interleukin-11 ELISA Kit
MBS2884259-03 5x 96 Well

Mouse Interleukin-11 ELISA Kit

Sign In for Pricing
View Details
Mouse Interleukin-11 ELISA Kit
MBS2884259-04 10x 96 Well

Mouse Interleukin-11 ELISA Kit

Sign In for Pricing
View Details
KCNC1 (NM_001112741) Human Tagged ORF Clone Lentiviral Particle
RC225985L4V 200 µL

KCNC1 (NM_001112741) Human Tagged ORF Clone Lentiviral Particle

Sign In for Pricing
View Details