L-Pyroglutamic acid (sodium)

L-Pyroglutamic acid sodium is the levo-isomer of Pyroglutamic acid. L-Pyroglutamic acid sodium is the biologically active enantiomer in humans. Pyroglutamic acid is an intermediate in glutathione metabolism. L-Pyroglutamic acid sodium can be used as a biomarker for systemic lupus erythematosus (SLE) [1].

Product Specifications

CAS Number

[28874-51-3]

UNSPSC

12352200

Hazard Statement

H272-H315-H319

Target

Endogenous Metabolite

Type

Biochemical Assay Reagents

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/l-pyroglutamic-acid-sodium.html

Solubility

10 mM in DMSO

Smiles

O=C(O[Na])[C@H](CC1)NC1=O

Molecular Formula

C5H6NNaO3

Molecular Weight

151.10

Precautions

P210-P220-P264-P280-P302+P352-P362+P364-P370+P378-P501

References & Citations

[1]Jiménez-Arias D, et al. Lettuce plants treated with L-pyroglutamic acid increase yield under water deficit stress[J]. Environmental and experimental botany, 2019, 158: 215-222.|[2]Zhang Q, et al., Metabolomic profiling reveals serum L-pyroglutamic acid as a potential diagnostic biomarker for systemic lupus erythematosus. Rheumatology (Oxford) . 2021 Feb 1;60 (2) :598-606.