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Maleic hydrazide-d2

Maleic hydrazide-d2 is the deuterium labeled Maleic hydrazide[1]. Maleic hydrazide is extensively used as a systemic plant growth regulator and as a herbicide. Maleic hydrazide acts as an inhibitor of the synthesis of nucleic acids and proteins[2][3].

Product Specifications

CAS Number

2398483-97-9

UNSPSC

12352005

Hazard Statement

H315, H319, H335, H341

Target

DNA/RNA Synthesis

Type

Isotope-Labeled Compounds

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Purity

99.31

Solubility

10 mM in DMSO

Smiles

O=C1C([2H])=C([2H])C(NN1)=O

Molecular Formula

C4H2D2N2O2

Molecular Weight

114.10

Precautions

H315, H319, H335, H341

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Venezian A, et al. The Influence of the Plant Growth Regulator Maleic Hydrazide on Egyptian Broomrape Early Developmental Stages and Its Control Efficacy in Tomato under Greenhouse and Field Conditions. Front Plant Sci. 2017;8:691. Published 2017 May 16.|[3]Swietlińska Z, et al. Cytotoxic effects of maleic hydrazide. Mutat Res. 197855 (1) :15-30.|[4]Yurdakok B, et al. Cytotoxic effects of etephon and maleic hydrazide in Vero, Hep2, HepG2 cells. Drug Chem Toxicol. 201437 (4) :459-465.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Isotope-Labeled Compounds

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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