BW A868C
BW A868C, a hydantoin compound, is a BW245C structural analogue. BW A868C is a selective and potent competitive prostaglandin D2 (PGD2) antagonist. BW A868C has no effect on other prostaglandin receptors (IP, EP1, EP2, TP and FP) [1].
Product Specifications
CAS Number
118675-50-6
UNSPSC
12352005
Hazard Statement
H225, H319, H350
Target
Prostaglandin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/bw-a868c.html
Concentration
21.76 mM * 100 μL in Ethanol
Purity
99.00
Solubility
10 mM in DMSO
Smiles
O=C(CCCCCCC1C(N(CC2=CC=CC=C2)C(N1NCC(C3CCCCC3)O)=O)=O)O
Molecular Formula
C25H37N3O5
Molecular Weight
459.58
Precautions
H225, H319, H350
References & Citations
[1]H Giles, et al. The classification of prostaglandin DP-receptors in platelets and vasculature using BW A868C, a novel, selective and potent competitive antagonist. Br J Pharmacol. 1989 Feb;96 (2) :291-300.
Shipping Conditions
Blue Ice
Storage Conditions
Solution, -20°C, 2 years
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
DP
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