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Ispinesib-d5

Ispinesib-d5 (SB-715992-d5) is a deuterium labeled Ispinesib. Ispinesib is a specific inhibitor of kinesin spindle protein (KSP).

Product Specifications

Product Name Alternative

SB-715992-d5

UNSPSC

12352005

Target

Apoptosis; Kinesin

Type

Isotope-Labeled Compounds

Related Pathways

Apoptosis; Cell Cycle/DNA Damage; Cytoskeleton

Applications

Cancer-programmed cell death

Field of Research

Cancer

Solubility

10 mM in DMSO

Smiles

O=C1N(CC2=C([2H])C([2H])=C([2H])C([2H])=C2[2H])C([C@@H](C(C)C)N(CCCN)C(C3=CC=C(C)C=C3)=O)=NC4=CC(Cl)=CC=C14

Molecular Formula

C30H28D5ClN4O2

Molecular Weight

522.09

References & Citations

[1]Purcell JW, et al. Activity of the kinesin spindle protein inhibitor ispinesib (SB-715992) in models of breast cancer. Clin Cancer Res. 2010 Jan 15;16 (2) :566-76.

Shipping Conditions

Room temperature

Scientific Category

Isotope-Labeled Compounds

Clinical Information

No Development Reported

Frequently Asked Questions

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