Fmoc-Gly-Gly- (D-Phe) -Gly-CH2-O-CH2-Cbz

Fmoc-Gly-Gly- (D-Phe) -Gly-CH2-O-CH2-Cbz is a PROTAC linker and a maleimide-GGFG peptide linker. Fmoc-Gly-Gly- (D-Phe) -Gly-CH2-O-CH2-Cbz can be used in the synthesis of the Deruxtecan[1].

Product Specifications

UNSPSC

12352005

Target

PROTAC Linkers

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/fmoc-gly-gly-d-phe-gly-ch2-o-ch2-cbz.html

Purity

95.1

Solubility

10 mM in DMSO

Smiles

O=C(OCC1=CC=CC=C1)COCNC(CNC([C@@H](CC2=CC=CC=C2)NC(CNC(CNC(OCC3C4=C(C=CC=C4)C5=C3C=CC=C5)=O)=O)=O)=O)=O

Molecular Formula

C40H41N5O9

Molecular Weight

735.78

References & Citations

[1]NOGUCHI, Shigeru, et al. Method for selectively manufacturing antibody-drug conjugate. WO2017002776A1.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

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