CbzNH-PEG8-amide-bis (pentayl-5OBz)
CbzNH-PEG8-amide-bis (pentayl-5OBz) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
Product Specifications
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
ADC Linker
Type
Reference compound
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cbznh-peg8-amide-bis-pentayl-5obz.html
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(N[C@H](C(NC[C@H](OC(C1=CC=CC=C1)=O)[C@@H](OC(C2=CC=CC=C2)=O)[C@H](OC(C3=CC=CC=C3)=O)[C@H](OC(C4=CC=CC=C4)=O)COC(C5=CC=CC=C5)=O)=O)CCC(NC[C@H](OC(C6=CC=CC=C6)=O)[C@@H](OC(C7=CC=CC=C7)=O)[C@H](OC(C8=CC=CC=C8)=O)[C@H](OC(C9=CC=CC=C9)=O)COC(C%10=CC=CC=C%10)=O)=O)CCOCCOCCOCCOCCOCCOCCOCCOCCNC(OCC%11=CC=CC=C%11)=O
Molecular Formula
C114H118N4O33
Molecular Weight
2072.16
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Stephanie Baah, et al. Antibody-Drug Conjugates-A Tutorial Review. Molecules. 2021 May 15;26 (10) :2943.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Cleavable Linker
Curated Selection
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