Genevant CL1 (monohydrochloride)
Genevant CL1 monohydrochloride is an ionizable lipid (lipid 10, pKa=6.3), and it can be used for mRNA lipid nanoparticle (LNP) vaccine delivery[1][2].
Product Specifications
UNSPSC
12352200
Target
Liposome
Type
Biochemical Assay Reagents
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/genevant-cl1-monohydrochloride.html
Solubility
10 mM in DMSO
Smiles
CN(C)CCCCC(OC(CCC/C=C\CCCCC)C(CCC/C=C\CCCCC)CCC/C=C\CCCCC)=O.[H]Cl
Molecular Formula
C39H74ClNO2
Molecular Weight
624.46
References & Citations
[1]Lam K, Leung A, Martin A, et al. Unsaturated, Trialkyl Ionizable Lipids are Versatile Lipid-Nanoparticle Components for Therapeutic and Vaccine Applications. Adv Mater. 2023;35 (15) :e2209624.|[2]Michael D Buschmann, et al. Nanomaterial Delivery Systems for mRNA Vaccines. Vaccines (Basel) . 2021 Jan 19;9 (1) :65.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-46759A/Genevant-CL1-monohydrochloride-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-46759A/
Scientific Category
Biochemical Assay Reagents
Clinical Information
No Development Reported
Curated Selection
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