Genevant CL1 (monohydrochloride)

Genevant CL1 monohydrochloride is an ionizable lipid (lipid 10, pKa=6.3), and it can be used for mRNA lipid nanoparticle (LNP) vaccine delivery[1][2].

Product Specifications

UNSPSC

12352200

Target

Liposome

Type

Biochemical Assay Reagents

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/genevant-cl1-monohydrochloride.html

Solubility

10 mM in DMSO

Smiles

CN(C)CCCCC(OC(CCC/C=C\CCCCC)C(CCC/C=C\CCCCC)CCC/C=C\CCCCC)=O.[H]Cl

Molecular Formula

C39H74ClNO2

Molecular Weight

624.46

References & Citations

[1]Lam K, Leung A, Martin A, et al. Unsaturated, Trialkyl Ionizable Lipids are Versatile Lipid-Nanoparticle Components for Therapeutic and Vaccine Applications. Adv Mater. 2023;35 (15) :e2209624.|[2]Michael D Buschmann, et al. Nanomaterial Delivery Systems for mRNA Vaccines. Vaccines (Basel) . 2021 Jan 19;9 (1) :65.