DMT-2'Fluoro-DG (IB) Amidite
DMT-2'Fluoro-DG (IB) Amidite (2'-F-ibu-dG Phosphoramidite) is a nucleoside. DMT-2'Fluoro-DG (IB) Amidite can be used to prepare 4'-modified 2'-deoxy-2'-fluorouridine[1].
Product Specifications
CAS Number
144089-97-4
Product Name Alternative
2'-F-ibu-dG Phosphoramidite
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
Nucleoside Antimetabolite/Analog
Type
Oligonucleotides
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/dmt-2-fluoro-dg-ib-amidite.html
Purity
99.45
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
COC(C=C1)=CC=C1C(C2=CC=C(C=C2)OC)(C3=CC=CC=C3)OC[C@@H]4[C@@H](OP(N(C(C)C)C(C)C)OCCC#N)[C@@H](F)[C@H](N5C=NC6=C5NC(NC(C(C)C)=O)=NC6=O)O4
Molecular Formula
C44H53FN7O8P
Molecular Weight
857.91
Precautions
H315, H319, H335
References & Citations
[1]Elise Malek-Adamian, et al. 4'-C-Methoxy-2'-deoxy-2'-fluoro Modified Ribonucleotides Improve Metabolic Stability and Elicit Efficient RNAi-Mediated Gene Silencing. J Am Chem Soc. 2017 Oct 18;139 (41) :14542-14555.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light)
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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