DMT-2'Fluoro-DG (IB) Amidite

DMT-2'Fluoro-DG (IB) Amidite (2'-F-ibu-dG Phosphoramidite) is a nucleoside. DMT-2'Fluoro-DG (IB) Amidite can be used to prepare 4'-modified 2'-deoxy-2'-fluorouridine[1].

Product Specifications

CAS Number

[144089-97-4]

Product Name Alternative

2'-F-ibu-dG Phosphoramidite

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

Nucleoside Antimetabolite/Analog

Type

Oligonucleotides

Related Pathways

Cell Cycle/DNA Damage

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/dmt-2-fluoro-dg-ib-amidite.html

Purity

99.45

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

COC(C=C1)=CC=C1C(C2=CC=C(C=C2)OC)(C3=CC=CC=C3)OC[C@@H]4[C@@H](OP(N(C(C)C)C(C)C)OCCC#N)[C@@H](F)[C@H](N5C=NC6=C5NC(NC(C(C)C)=O)=NC6=O)O4

Molecular Formula

C44H53FN7O8P

Molecular Weight

857.91

Precautions

H315, H319, H335

References & Citations

[1]Elise Malek-Adamian, et al. 4'-C-Methoxy-2'-deoxy-2'-fluoro Modified Ribonucleotides Improve Metabolic Stability and Elicit Efficient RNAi-Mediated Gene Silencing. J Am Chem Soc. 2017 Oct 18;139 (41) :14542-14555.