M-C-tri (CH2-PEG1-NHS ester)
M-C-tri (CH2-PEG1-NHS ester) is a non-cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1].
Product Specifications
CAS Number
[173414-89-6]
UNSPSC
12352203
Hazard Statement
H302, H315, H319, H335
Target
ADC Linker
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/m-c-tri-ch2-peg1-nhs-ester.html
Purity
97.0
Solubility
10 mM in DMSO
Smiles
CC(COCCC(ON1C(CCC1=O)=O)=O)(COCCC(ON2C(CCC2=O)=O)=O)COCCC(ON3C(CCC3=O)=O)=O
Molecular Formula
C26H33N3O15
Molecular Weight
627.55
Precautions
H302, H315, H319, H335
References & Citations
[1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16 (5) :315-337.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Non-cleavable Linker
Available Sizes
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