Chlorthalidone impurity
Chlorthalidone impurity is a metabolite of Chlorthalidone (HY-15833) . Chlorthalidone is a thiazide-like diuretic used to treat hypertension[1][2].
Product Specifications
CAS Number
[5270-74-6]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Drug Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/chlorthalidone-impurity.html
Purity
99.68
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=C(O)C1=CC=CC=C1C(C2=CC=C(Cl)C(S(=O)(N)=O)=C2)=O
Molecular Formula
C14H10ClNO5S
Molecular Weight
339.75
Precautions
H302, H315, H319, H335
References & Citations
[1]Bauer J, et al. Stability-indicating assay for chlorthalidone formulation: evaluation of the USP analysis and a high-performance liquid chromatographic analysis. J Pharm Sci. 1983 Aug;72 (8) :924-8.|[2]Barrios V, et al. Which thiazide to choose as add-on therapy for hypertension? Integr Blood Press Control. 2014 Jul 30;7:35-47.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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