Taltobulin intermediate-8
Taltobulin intermediate-8 is an intermediate in the synthesis of Taltobulin (HY-15584) . Taltobulin is a common toxin component in ADC preparation (ADC Cytotoxin), and it is also a powerful tubulin (Microtubule/Tubulin) inhibitor. Taltobulin disrupts tubulin polymerization, induces mitotic arrest, and induces apoptosis[1].
Product Specifications
CAS Number
[676487-38-0]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
ADC Payload; Microtubule/Tubulin
Type
Reference compound
Related Pathways
Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage; Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/taltobulin-intermediate-8.html
Purity
98.08
Solubility
10 mM in DMSO
Smiles
OC([C@H](N(C(OC(C)(C)C)=O)C)C(C)(C)C1=CC=CC=C1)=O
Molecular Formula
C17H25NO4
Molecular Weight
307.38
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-41070/Taltobulin-intermediate-8-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-41070/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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