NH2-C4-NH-Boc
NH2-C4-NH-Boc (compound 15) is a PROTAC linker, which refers to the Alkyl/ether composition. NH2-C4-NH-Boc can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
Product Specifications
CAS Number
68076-36-8
UNSPSC
12352211
Hazard Statement
H314, H318
Target
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/nh2-c4-nh-boc.html
Purity
99.98
Solubility
H2O : 100 mg/mL (ultrasonic)
Smiles
NCCCCNC(OC(C)(C)C)=O
Molecular Formula
C9H20N2O2
Molecular Weight
188.27
Precautions
H314, H318
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light, stored under nitrogen)
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Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Alkyl/ether Linkers
Frequently Asked Questions
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