MC-GGFG-AM- (10Me-11F-Camptothecin) intermediate-1

MC-GGFG-AM- (10Me-11F-Camptothecin) intermediate-1 (compound 19-2) is an intermediate for the synthesis of MC-GGFG-AM- (10Me-11F-Camptothecin) (HY-153360) . Modifying groups can be added group. MC-GGFG-AM- (10Me-11F-Camptothecin) is a drug-linker conjugate used in the synthesis of ADCs[1].

Product Specifications

CAS Number

[1241391-14-9]

Product Name Alternative

1- (2-Amino-4-fluoro-5-methylphenyl) -2-chloroethanone

UNSPSC

12352203

Hazard Statement

H302, H315, H319, H335

Target

Drug-Linker Conjugates for ADC; Topoisomerase

Type

Reference compound

Related Pathways

Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/mc-ggfg-am-10me-11f-camptothecin-intermediate-1.html

Purity

97.47

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

ClCC(C1=CC(C)=C(F)C=C1N)=O

Molecular Formula

C9H9ClFNO

Molecular Weight

201.63

Precautions

H302, H315, H319, H335

References & Citations

[1]Jiangsu Simcere Pharmaceutical, et al. Camptothecin derivative, and pharmaceutical composition and use thereof. World Intellectual Property Organization, WO2023020605 A1 2023-02-23.