[Hydroxy (tosyloxy) iodo]benzene

[Hydroxy (tosyloxy) iodo]benzene is a versatile reagent for the mild oxidation of aryl iodides at the iodine atom by ligand transfer. [Hydroxy (tosyloxy) iodo]benzene is an effective reagent for the one-step conversion of ketones to the corresponding α-tosyloxy ketones. [Hydroxy (tosyloxy) iodo]benzene is also a Bronsted acid and is expected to catalyze the enolization of ketones[1][2].

Product Specifications

CAS Number

[27126-76-7]

UNSPSC

12352200

Hazard Statement

H315, H319

Target

Biochemical Assay Reagents

Type

Biochemical Assay Reagents

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/hydroxy-tosyloxy-iodo-benzene.html

Purity

99.36

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

OI(C1=CC=CC=C1)OS(C2=CC=C(C)C=C2)(=O)=O

Molecular Formula

C13H13IO4S

Molecular Weight

392.21

Precautions

H315, H319

References & Citations

[1]Gerald F. Koser, et al., [Hydroxy (tosyloxy) iodo]benzene, a Versatile Reagent for the Mild Oxidation of Aryl Iodides at the Iodine Atom by Ligand Transfer. J. Org. Chem. 1980, 45, 1542-1543.|[2]Gerald F. Koser, et al., One-Step -Tosyloxylation of Ketones with [Hydroxy (tosyloxy) iodo]benzene. J. Org. Chem. 1982, 47, 2487-2489.