Elocalcitol
Product Specifications
UNSPSC Description
Elocalcitol (BXL-628) is a selective, orally active vitamin D receptor (VDR) agonist. Elocalcitol shows anti-inflammatory activity. Elocalcitol inhibits growth of prostate cancer cells[1][2].
Target Antigen
VD/VDR
Type
Reference compound
Related Pathways
Vitamin D Related/Nuclear Receptor
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/elocalcitol.html
Purity
99.2
Solubility
DMSO : 30 mg/mL (ultrasonic;warming)
Smiles
C[C@@]12[C@](CC=C2[C@@H](C)C/C=C/C(CC)(O)CC)([H])/C(CCC1)=C/C=C3C([C@H](C[C@@H](C\3)O)F)=C
Molecular Weight
442.65
References & Citations
[1]Mariani M, et al. The selective vitamin D receptor agonist, elocalcitol, reduces endometriosis development in a mouse model by inhibiting peritoneal inflammation. Hum Reprod. 2012 Jul;27(7):2010-9. |[2]Marchiani S, et al. The vitamin D analogue BXL-628 inhibits growth factor-stimulated proliferation and invasion of DU145 prostate cancer cells. J Cancer Res Clin Oncol. 2006 Jun;132(6):408-16.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-32345/Elocalcitol-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-32345/Elocalcitol-SDS-MedChemExpress.pdf
Clinical Information
Phase 2
CAS Number
199798-84-0
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