α-Eleostearic acid

α-Eleostearic acid (cis-Eleostearic acid), a conjugated linolenic acid, is an apoptosis inducer. α-Eleostearic acid is also a ferroptosis inducer. α-Eleostearic acid exhibits antioxidant and antitumor activity[1][2][3].

Product Specifications

CAS Number

[506-23-0]

Product Name Alternative

Cis-Eleostearic acid

UNSPSC

12352211

Hazard Statement

H225, H301+H311+H331, H370

Target

Apoptosis; Ferroptosis

Type

Reference compound

Related Pathways

Apoptosis

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Cancer; Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/α-eleostearic-acid.html

Concentration

35.92 mM * 100 μL in Methanol

Purity

98.00

Solubility

10 mM in DMSO

Smiles

CCCC/C=C/C=C/C=C\CCCCCCCC(O)=O

Molecular Formula

C18H30O2

Molecular Weight

278.43

Precautions

H225, H301+H311+H331, H370

References & Citations

[1]Kobori M, et, al. Alpha-eleostearic acid and its dihydroxy derivative are major apoptosis-inducing components of bitter gourd. J Agric Food Chem. 2008 Nov 26;56 (22) :10515-20.|[2]Saha SS, et, al. Comparative study of antioxidant activity of alpha-eleostearic acid and punicic acid against oxidative stress generated by sodium arsenite. Food Chem Toxicol. 2009 Oct;47 (10) :2551-6. |[3]Beatty A, et, al. Ferroptotic cell death triggered by conjugated linolenic acids is mediated by ACSL1. Nat Commun. 2021 Apr 14;12 (1) :2244.