α-Eleostearic acid
α-Eleostearic acid (cis-Eleostearic acid), a conjugated linolenic acid, is an apoptosis inducer. α-Eleostearic acid is also a ferroptosis inducer. α-Eleostearic acid exhibits antioxidant and antitumor activity[1][2][3].
Product Specifications
CAS Number
506-23-0
Product Name Alternative
Cis-Eleostearic acid
UNSPSC
12352211
Hazard Statement
H225, H301+H311+H331, H370
Target
Apoptosis; Ferroptosis
Type
Reference compound
Related Pathways
Apoptosis
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Cancer; Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/α-eleostearic-acid.html
Concentration
35.92 mM * 100 μL in Methanol
Purity
98.00
Solubility
10 mM in DMSO
Smiles
CCCC/C=C/C=C/C=C\CCCCCCCC(O)=O
Molecular Formula
C18H30O2
Molecular Weight
278.43
Precautions
H225, H301+H311+H331, H370
References & Citations
[1]Kobori M, et, al. Alpha-eleostearic acid and its dihydroxy derivative are major apoptosis-inducing components of bitter gourd. J Agric Food Chem. 2008 Nov 26;56 (22) :10515-20.|[2]Saha SS, et, al. Comparative study of antioxidant activity of alpha-eleostearic acid and punicic acid against oxidative stress generated by sodium arsenite. Food Chem Toxicol. 2009 Oct;47 (10) :2551-6. |[3]Beatty A, et, al. Ferroptotic cell death triggered by conjugated linolenic acids is mediated by ACSL1. Nat Commun. 2021 Apr 14;12 (1) :2244.
Shipping Conditions
Dry Ice
Storage Conditions
-80°C
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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