Homopterocarpin
Product Specifications
UNSPSC Description
Homopterocarpin is an isoflavonoid that can be isolated from Pterocarpus erinaceus. Homopterocarpin has hepatoprotective and antioxidant properties. Homopterocarpin is a competitive reversible inhibitor of human monoamine oxidase-B with an IC50 and a Ki of 0.72 and 0.21 μM for hMAO-B, respectively. Homopterocarpin can be used for the research of liver injury and oxidative stress[1][2].
Target Antigen
Monoamine Oxidase
Type
Natural Products
Related Pathways
Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/homopterocarpin.html
Solubility
10 mM in DMSO
Smiles
COC1=CC=C([C@@]2([H])[C@@](C3=CC=C(OC)C=C3O2)([H])CO4)C4=C1
Molecular Weight
284.31
References & Citations
[1]Akinmoladun AC, et al. Effect of homopterocarpin, an isoflavonoid from Pterocarpus erinaceus, on indices of liver injury and oxidative stress in acetaminophen-provoked hepatotoxicity. J Basic Clin Physiol Pharmacol. 2015 Nov;26(6):555-62. |[2]Oh JM, et al. Medicarpin and Homopterocarpin Isolated from Canavalia lineata as Potent and Competitive Reversible Inhibitors of Human Monoamine Oxidase-B. Molecules. 2022 Dec 28;28(1):258.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-N4037/Homopterocarpin-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-N4037/
Clinical Information
No Development Reported
CAS Number
606-91-7
Available Sizes
Curated Selection
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