(±) -Darifenacin-d4

(±) -Darifenacin-d4 is deuterium labeled (±) -Darifenacin. (±) -Darifenacin is the racemate of Darifenacin. Darifenacin is a selective M3 muscarinic receptor antagonist[1].

Product Specifications

CAS Number

[1189701-43-6]

Product Name Alternative

(±) -UK-88525-d4

UNSPSC

12352005

Hazard Statement

H302+H312+H332-H315-H319

Target

Isotope-Labeled Compounds; mAChR

Type

Isotope-Labeled Compounds

Related Pathways

GPCR/G Protein; Neuronal Signaling; Others

Applications

Cancer-programmed cell death

Field of Research

Cancer; Neurological Disease

Solubility

10 mM in DMSO

Smiles

NC(C(C1=CC=CC=C1)(C2=CC=CC=C2)C3CN(CC3)C([2H])([2H])C([2H])([2H])C4=CC=C(OCC5)C5=C4)=O

Molecular Formula

C28H26D4N2O2

Molecular Weight

430.57

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P501

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Hegde SS, et al. Functional role of M2 and M3 muscarinic receptors in the urinary bladder of rats in vitro and in vivo. Br J Pharmacol, 1997, 120 (8), 1409-1418.