6-Chloro-2-iodopurine-9-riboside
Product Specifications
UNSPSC Description
9H-Purine, 6-chloro-2-iodo-9-β-D-ribofuranosyl- (6-CHLORO-2-IODOPURINE-9-RIBOSIDE) is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Target Antigen
Nucleoside Antimetabolite/Analog
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/6-chloro-2-iodopurine-9-riboside.html
Solubility
10 mM in DMSO
Smiles
ClC1=C(N=CN2[C@H]3[C@H](O)[C@H](O)[C@@H](CO)O3)C2=NC(I)=N1
Molecular Weight
412.57
References & Citations
[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-21978/6-Chloro-2-iodopurine-9-riboside-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-21978/
Clinical Information
No Development Reported
CAS Number
313477-85-9
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