Mc-Val-Cit-PABC-PNP (GMP)
Product Specifications
UNSPSC Description
Mc-Val-Cit-PABC-PNP GMP is a GMP grade Mc-Val-Cit-PABC-PNP (HY-20336). Mc-Val-Cit-PABC-PNP is a cathepsin cleavable ADC linker. Mc-Val-Cit-PABC-PNP can be used in the synthesis of antibody-drug conjugates (ADCs)[1].
Target Antigen
ADC Linker
Type
GMP Small Molecules
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mc-val-cit-pabc-pnp-gmp.html
Solubility
10 mM in DMSO
Smiles
CC(C)[C@@H](C(N[C@@H](CCCNC(N)=O)C(NC1=CC=C(COC(OC2=CC=C([N+]([O-])=O)C=C2)=O)C=C1)=O)=O)NC(CCCCCN3C(C=CC3=O)=O)=O
Molecular Weight
737.76
References & Citations
[1]Che-Leung Law et al. Anti-cd70 antibody-drug conjugates and their use for the treatment of cancer and immune disorders.Patent WO2005081711A2.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-20336G/Mc-Val-Cit-PABC-PNP-GMP-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-20336G/
Clinical Information
No Development Reported
CAS Number
159857-81-5
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