Contezolid acefosamil

Contezolid acefosamil (MRX-4) is the orally active proagent of the active antimicrobial metabolite Contezolid (MRX-I), an oxazolidinone which shows potent in vitro activity against various multidrug-resistant Gram-positive bacteria, including MRSA[1].

Product Specifications

CAS Number

[1807497-11-5]

Product Name Alternative

MRX-4

UNSPSC

12352005

Target

Antibiotic; Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/contezolid-acefosamil.html

Solubility

10 mM in DMSO

Smiles

FC(C(F)=C1N(C=C2)CCC2=O)=C(N(C(O3)=O)C[C@@H]3CN(C4=NOC=C4)[P](OC(C)=O)(O)=O)C=C1F

Molecular Formula

C20H18F3N4O8P

Molecular Weight

530.35

References & Citations

[1]Matteo Bassetti, et al. Innovative therapies for acute bacterial skin and skin-structure infections (ABSSSI) caused by methicillin-resistant Staphylococcus aureus: advances in phase I and II trials. Expert Opin Investig Drugs. 2020 May;29 (5) :495-506.