GSK1521498
GSK1521498 is a potent and selective μ-opioid receptor (MOR) antagonist. GSK1521498 has the potential for disorders of compulsive consumption of food, alcohol, and agents[1].
Product Specifications
CAS Number
1426543-84-1
UNSPSC
12352005
Target
Opioid Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/gsk1521498.html
Solubility
10 mM in DMSO
Smiles
FC1=C(CNC2CC3=C(C=CC=C3)C2)C(F)=CC(C4=CC=CC(C5=NC=NN5)=C4)=C1.O=P(O)(O)O
Molecular Formula
C24H23F2N4O4P
Molecular Weight
500.43
References & Citations
[1]Giuliano C, et al. The Novel μ-Opioid Receptor Antagonist GSK1521498 Decreases Both Alcohol Seeking and Drinking: Evidence from a New Preclinical Model of Alcohol Seeking. Neuropsychopharmacology. 2015 Dec;40 (13) :2981-92.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2
Isoform
μ Opioid Receptor/MOR
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
A00253-1-Fluoro647 100 µg/Vial
Anti-Heme Oxygenase 1/Hmox1 Antibody Picoband® Fluoro647 Conjugated
Sign In for Pricing
View Details 
253720-HRP 100 µL
ZNF274 (Zinc Finger Protein 274, DKFZp686K08243, FLJ37843, HFB101, ZF2, ZKSCAN19) (HRP)
Sign In for Pricing
View Details MBS2050176-01 0.1 mL
APC/CY7-Linked Polyclonal Antibody to Cyclophilin A (CYPA)
Sign In for Pricing
View Details