What is the catalog number for Sandramycin?

The catalog number for Sandramycin is HY-19829.

What sizes are available for Sandramycin?

Sandramycin is available in the following size(s): 1 mg.

Is Sandramycin in stock?

Sandramycin is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Sandramycin?

Sandramycin is manufactured by QuantiMol.

What is the estimated delivery time for Sandramycin?

Estimated delivery time for Sandramycin is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Sandramycin?

The safety data sheet for Sandramycin is available here: http://file.medchemexpress.com/batch_PDF/HY-19829/.

Sandramycin

Sandramycin ia a cyclic depsipeptide antibiotic isolated from cultured broth of a Nocardioides sp. Sandramycin is also a DNA intercalator that potently binds DNA and is an ADC cytotoxin. Sandramycin is active against Gram-positive bacteria and has potent antitumor activity[1][2][3].

Product Specifications

CAS Number

100940-65-6

UNSPSC

12352005

Target

ADC Payload; Antibiotic; Bacterial

Type

Natural Products

Related Pathways

Antibody-drug Conjugate/ADC Related; Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Infection

Assay Protocol

https://www.medchemexpress.com/sandramycin.html

Solubility

10 mM in DMSO

Smiles

CC(C)[C@@H](C(OC[C@@H](NC(C1=C(O)C=C(C=CC=C2)C2=N1)=O)C3=O)=O)N(C)C(CN(C)C(CNC([C@@H]4CCCCN4C([C@@H](COC([C@H](C(C)C)N(C)C(CN(C)C(CNC([C@H]5N3CCCC5)=O)=O)=O)=O)NC(C6=C(O)C=C(C=CC=C7)C7=N6)=O)=O)=O)=O)=O

Molecular Formula

C60H76N12O16

Molecular Weight

1221.32

References & Citations

[1]J A Matson, et al. Sandramycin, a Novel Antitumor Antibiotic Produced by a Nocardioides Sp. Production, Isolation, Characterization and Biological Properties. J Antibiot (Tokyo) . 1989 Dec;42 (12) :1763-7.|[2]Katsushi Katayama, et al. Total Synthesis of Sandramycin and Its Analogues via a Multicomponent Assemblage. Org Lett. 2014 Jan 17;16 (2) :428-31.|[3]D L Boger, et al. DNA Binding Properties of Key Sandramycin Analogues: Systematic Examination of the Intercalation Chromophore. Bioorg Med Chem. 1999 Feb;7 (2) :315-21.