4-Butyl-alpha-agarofuran

4-Butyl-alpha-agarofuran (AF 5) is an anxiolytic and antidepressant agent. 4-Butyl-alpha-agarofuran a α-agarofuran derivative that can be isolated from Gharu-wood. 4-Butyl-alpha-agarofuran can be used for the research of neurological disease research[1].

Product Specifications

CAS Number

[272126-07-5]

Product Name Alternative

Buagafuran; Buagarofuran

UNSPSC

12352005

Target

5-HT Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/4-butyl-alpha-agarofuran.html

Purity

98.0

Solubility

10 mM in DMSO

Smiles

C[C@]12CC[C@@](C3)([H])C(C)(C)O[C@@]13C(CCCC)=CCC2

Molecular Formula

C18H30O

Molecular Weight

262.43

References & Citations

[1]Zhang Y, et al. Effects of novel anxiolytic 4-butyl-alpha-agarofuran on levels of monoamine neurotransmitters in rats. Eur J Pharmacol. 2004 Nov 3;504 (1-2) :39-44.|[2]Li N, et al. [In vitro metabolic studies of the novel anti-anxietic drug AF-5 and its metabolites in human liver microsome incubation system]. Yao Xue Xue Bao. 2001 Jul;36 (7) :528-31. Chinese.