Iroxanadine (sulfate)
Iroxanadine (BRX 005) sulfate is a vasculoprotector. Iroxanadine is a p38 kinase and HSP protein dual activator. Iroxanadine sulfate has the potential for atherosclerosis and vascular diseases research[1].
Product Specifications
CAS Number
276690-61-0
Product Name Alternative
(-) -BRX 005 (sulfate) ; (-) -BRX 235 (sulfate)
UNSPSC
12352005
Target
HSP; p38 MAPK
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; MAPK/ERK Pathway; Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/iroxanadine-sulfate.html
Solubility
10 mM in DMSO
Smiles
O=S(O)(O)=O.C1(NC(C2=CN=CC=C2)=NOC1)CN3CCCCC3
Molecular Formula
C14H22N4O5S
Molecular Weight
358.41
References & Citations
[1]Denes L, et al. Reverse regulation of endothelial cells and myointimal hyperplasia on cell proliferation by a heatshock protein-coinducer after hypoxia. Stroke. 2008 Mar;39 (3) :1022-4.|[2]Kabakov AE, et al. Pharmacological attenuation of apoptosis in reoxygenated endothelial cells. Cell Mol Life Sci. 2004 Dec;61 (24) :3076-86.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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